Errol Gould
Seminars
Wednesday 27th January 2027
Panel Discussion: Solving the Placebo Problem in Chronic Pain Trials
3:30 pm
- Reduce placebo inflation through protocol design and site management
- Improve patient training and consistency across sites
- Examine crossover and adaptive study designs
- Apply lessons from successful recent programs
Wednesday 27th January 2027
Managing Benefit Expectations: How Participant Education Mitigates Placebo Response in Chronic Pain Trials
4:00 pm
- Explain how expectations of benefit can influence placebo responses and outcomes in chronic pain trials
- Describe participant-education strategies designed to establish realistic expectations without compromising informed consent or engagement
- Evaluate how expectation-management interventions may improve trial validity, signal detection, and interpretation of treatment effects
