Potassium Channels as the Next Major Opportunity in Pain Therapeutics
2:00 pm - Thursday 28th January 2027
- Understanding how Kv7 potassium channel activation reduces neuronal hyperexcitability to suppress pain signalling at its source
- Leveraging lessons from clinically validated Kv7 programs to accelerate development in pain indications
- Understanding the scientific rationale for pairing selective NaV1.7 inhibition with Kv7.2/7.3 activation to more effectively reduce sensory neuron hyperexcitability
- Assessing the long-term potential of Kv7 activators across neuropathic, inflammatory and musculoskeletal pain populations